Plasma and tissue levels of dietary radiotocopherols in the harp seal, Phoca groenlandica

• Published in: Canadian Journal of Physiology and Pharmacology
• Main Author: Engelhardt, F. R.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Canadian Science Publishing 1977
• Subjects: Physiology (medical); Pharmacology; General Medicine; Physiology; Harp Seal; Phoca groenlandica
• Online Access: http://dx.doi.org/10.1139/y77-083; http://www.nrcresearchpress.com/doi/pdf/10.1139/y77-083

Plasma and tissue levels of dietary radiotracer-labelled tocopherols were examined in the harp seal, Phoca groenlandica. The d-α form showed much higher plasma maxima and retention than d,l-γ-tocopherol. Concentration peaks occurred somewhat later but were greater when the vitamin was fed with Tween 80 than with herring and corn oil respectively. Greater plasma levels occurred with the use of herring oil as compared with corn oil. Seals previously maintained on a vitamin E deficient diet showed greater plasma maxima than seals not so deprived. Plasma and tissues generally showed maximum levels within 24 h postingestion. Tissue levels of labelled dietary α-tocopherol were examined by biopsy and postmortem studies in selected tissues of vitamin E deprived seals.