The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis
Procaine hydrochloride decreases potential and effective resistance of the membrane and does not produce prolonged spikes. Tetraethylammonium (TEA) and barium ions prolong the spikes of internodal cells of Nitella evidently by delaying K + activation as is the case in many other excitable cells. The...
Published in: | Canadian Journal of Physiology and Pharmacology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Canadian Science Publishing
1971
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Online Access: | http://dx.doi.org/10.1139/y71-113 http://www.nrcresearchpress.com/doi/pdf/10.1139/y71-113 |
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crcansciencepubl:10.1139/y71-113 2023-12-17T10:45:55+01:00 The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis Belton, P. Netten, C. Van 1971 http://dx.doi.org/10.1139/y71-113 http://www.nrcresearchpress.com/doi/pdf/10.1139/y71-113 en eng Canadian Science Publishing http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining Canadian Journal of Physiology and Pharmacology volume 49, issue 9, page 824-832 ISSN 0008-4212 1205-7541 Physiology (medical) Pharmacology General Medicine Physiology journal-article 1971 crcansciencepubl https://doi.org/10.1139/y71-113 2023-11-19T13:38:30Z Procaine hydrochloride decreases potential and effective resistance of the membrane and does not produce prolonged spikes. Tetraethylammonium (TEA) and barium ions prolong the spikes of internodal cells of Nitella evidently by delaying K + activation as is the case in many other excitable cells. The last two agents do not increase the amplitude of the spikes in contrast to their effect on some arthropod muscle fibers. The other effects of Ba 2+ and TEA on the spikes of Nitella and animal cells are almost identical. We conclude that the same molecular mechanism is involved in K + activation in animals and plants. Article in Journal/Newspaper Nitella flexilis Canadian Science Publishing (via Crossref) Canadian Journal of Physiology and Pharmacology 49 9 824 832 |
institution |
Open Polar |
collection |
Canadian Science Publishing (via Crossref) |
op_collection_id |
crcansciencepubl |
language |
English |
topic |
Physiology (medical) Pharmacology General Medicine Physiology |
spellingShingle |
Physiology (medical) Pharmacology General Medicine Physiology Belton, P. Netten, C. Van The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
topic_facet |
Physiology (medical) Pharmacology General Medicine Physiology |
description |
Procaine hydrochloride decreases potential and effective resistance of the membrane and does not produce prolonged spikes. Tetraethylammonium (TEA) and barium ions prolong the spikes of internodal cells of Nitella evidently by delaying K + activation as is the case in many other excitable cells. The last two agents do not increase the amplitude of the spikes in contrast to their effect on some arthropod muscle fibers. The other effects of Ba 2+ and TEA on the spikes of Nitella and animal cells are almost identical. We conclude that the same molecular mechanism is involved in K + activation in animals and plants. |
format |
Article in Journal/Newspaper |
author |
Belton, P. Netten, C. Van |
author_facet |
Belton, P. Netten, C. Van |
author_sort |
Belton, P. |
title |
The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
title_short |
The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
title_full |
The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
title_fullStr |
The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
title_full_unstemmed |
The Effects of Pharmacological Agents on the Electrical Responses of Cells of Nitella flexilis |
title_sort |
effects of pharmacological agents on the electrical responses of cells of nitella flexilis |
publisher |
Canadian Science Publishing |
publishDate |
1971 |
url |
http://dx.doi.org/10.1139/y71-113 http://www.nrcresearchpress.com/doi/pdf/10.1139/y71-113 |
genre |
Nitella flexilis |
genre_facet |
Nitella flexilis |
op_source |
Canadian Journal of Physiology and Pharmacology volume 49, issue 9, page 824-832 ISSN 0008-4212 1205-7541 |
op_rights |
http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining |
op_doi |
https://doi.org/10.1139/y71-113 |
container_title |
Canadian Journal of Physiology and Pharmacology |
container_volume |
49 |
container_issue |
9 |
container_start_page |
824 |
op_container_end_page |
832 |
_version_ |
1785569235342196736 |