Article

• Published in: Canadian Journal of Chemistry
• Main Authors: Avilov, Sergey A, Drozdova, Olga A, Kalinin, Vladimir I, Kalinovsky, Anatoly I, Stonik, Valentin A, Gudimova, Elena N, Riguera, Ricardo, Jiménez, Carlos
• Format: Article in Journal/Newspaper
• Language: English
• Published: Canadian Science Publishing 1998
• Subjects: Organic Chemistry; General Chemistry; Catalysis; Cucumaria frondosa
• Online Access: http://dx.doi.org/10.1139/v97-218; http://www.nrcresearchpress.com/doi/pdf/10.1139/v97-218

Frondoside C (1) is a new sulfated nonholostane triterpene glycoside obtained (with the glycosides closed by aglycone structure as impurities) from the sea cucumber Cucumaria frondosa. Its structure has been elucidated on the basis of spectral data (NMR and MS) of compound 1 and of its desulfated derivative (2) obtained by solvolysis. Frondoside C (1) is just the seventh glycoside reported from sea cucumbers, having a lanostane-type aglycone devoid of the typical 18(20)- lactone ring.Key words: Cucumaria frondosa, sea cucumbers, frondosides, triterepene glycosides, antitumor activity.