Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins
The gustatory responses to tetrodotoxin (TTX) and saxitoxin (STX) recorded from the palatine nerve (VIIth cranial nerve) were studied electrophysiological in rainbow trout (Salmo gairdneri) and Arctic char (Salvelinus alpinus). Both toxins were highly effective gustatory stimuli in both species, in...
Published in: | Canadian Journal of Fisheries and Aquatic Sciences |
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Canadian Science Publishing
1988
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Online Access: | http://dx.doi.org/10.1139/f88-253 http://www.nrcresearchpress.com/doi/pdf/10.1139/f88-253 |
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crcansciencepubl:10.1139/f88-253 2024-09-15T18:33:07+00:00 Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins Yamamori, Kunio Nakamura, Moritaka Matsui, Takashi Hara, Toshiaki j. 1988 http://dx.doi.org/10.1139/f88-253 http://www.nrcresearchpress.com/doi/pdf/10.1139/f88-253 en eng Canadian Science Publishing http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining Canadian Journal of Fisheries and Aquatic Sciences volume 45, issue 12, page 2182-2186 ISSN 0706-652X 1205-7533 journal-article 1988 crcansciencepubl https://doi.org/10.1139/f88-253 2024-08-22T04:08:45Z The gustatory responses to tetrodotoxin (TTX) and saxitoxin (STX) recorded from the palatine nerve (VIIth cranial nerve) were studied electrophysiological in rainbow trout (Salmo gairdneri) and Arctic char (Salvelinus alpinus). Both toxins were highly effective gustatory stimuli in both species, in rainbow trout, TTX had a threshold concentration 2 × 10 −7 mol/L and at 10 −5 mol/L evoked a response four times that of 10 −3 mol L-proline/L, the most potent amino acid for this species. The threshold for STX was Sower (10 −8 mol/L), but unlike TTX the response magnitude reached a maximum at 10 −6 mol/L. The reverse occurred in Arctic char; lower threshold for TTX (10 −8 mol/L) than STX (10 −7 mol/L) and the response magnitude never exceeded that of 10 −3 mol L-proline/L. Cross-adaptation experiments indicated that the receptor(s) for TTX are distinct from those which detect amino acids and bile salts and that TTX and STX do not share the same receptor populations. Furthermore, the integrated response to TTX or STX was a fast-adapting, phasic response and rapidly returned to baseline even with continued stimulation. Perfusion of the gustatory organs with these toxins had little toxic effect. The sensitive, specific gustatory receptor system for the toxins suggests the existence of a mechanism for avoiding poisonous prey organisms that has adaptive advantage to the receiver (predator). Article in Journal/Newspaper Salvelinus alpinus Canadian Science Publishing Canadian Journal of Fisheries and Aquatic Sciences 45 12 2182 2186 |
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Open Polar |
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Canadian Science Publishing |
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crcansciencepubl |
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English |
description |
The gustatory responses to tetrodotoxin (TTX) and saxitoxin (STX) recorded from the palatine nerve (VIIth cranial nerve) were studied electrophysiological in rainbow trout (Salmo gairdneri) and Arctic char (Salvelinus alpinus). Both toxins were highly effective gustatory stimuli in both species, in rainbow trout, TTX had a threshold concentration 2 × 10 −7 mol/L and at 10 −5 mol/L evoked a response four times that of 10 −3 mol L-proline/L, the most potent amino acid for this species. The threshold for STX was Sower (10 −8 mol/L), but unlike TTX the response magnitude reached a maximum at 10 −6 mol/L. The reverse occurred in Arctic char; lower threshold for TTX (10 −8 mol/L) than STX (10 −7 mol/L) and the response magnitude never exceeded that of 10 −3 mol L-proline/L. Cross-adaptation experiments indicated that the receptor(s) for TTX are distinct from those which detect amino acids and bile salts and that TTX and STX do not share the same receptor populations. Furthermore, the integrated response to TTX or STX was a fast-adapting, phasic response and rapidly returned to baseline even with continued stimulation. Perfusion of the gustatory organs with these toxins had little toxic effect. The sensitive, specific gustatory receptor system for the toxins suggests the existence of a mechanism for avoiding poisonous prey organisms that has adaptive advantage to the receiver (predator). |
format |
Article in Journal/Newspaper |
author |
Yamamori, Kunio Nakamura, Moritaka Matsui, Takashi Hara, Toshiaki j. |
spellingShingle |
Yamamori, Kunio Nakamura, Moritaka Matsui, Takashi Hara, Toshiaki j. Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
author_facet |
Yamamori, Kunio Nakamura, Moritaka Matsui, Takashi Hara, Toshiaki j. |
author_sort |
Yamamori, Kunio |
title |
Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
title_short |
Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
title_full |
Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
title_fullStr |
Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
title_full_unstemmed |
Gustatory Responses to Tetrodotoxin and Saxitoxin in Fish: A Possible Mechanism for Avoiding Marine Toxins |
title_sort |
gustatory responses to tetrodotoxin and saxitoxin in fish: a possible mechanism for avoiding marine toxins |
publisher |
Canadian Science Publishing |
publishDate |
1988 |
url |
http://dx.doi.org/10.1139/f88-253 http://www.nrcresearchpress.com/doi/pdf/10.1139/f88-253 |
genre |
Salvelinus alpinus |
genre_facet |
Salvelinus alpinus |
op_source |
Canadian Journal of Fisheries and Aquatic Sciences volume 45, issue 12, page 2182-2186 ISSN 0706-652X 1205-7533 |
op_rights |
http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining |
op_doi |
https://doi.org/10.1139/f88-253 |
container_title |
Canadian Journal of Fisheries and Aquatic Sciences |
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45 |
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12 |
container_start_page |
2182 |
op_container_end_page |
2186 |
_version_ |
1810474850605596672 |