Nutritional status and the gonadotrophic response to a polar expedition
Polar expeditions have been associated with changes in the hypothalamic–pituitary–testicular axis consistent with central hypogonadism (i.e., decreased testosterone, luteinising hormone (LH), and follicle stimulating hormone (FSH)). These changes are typically associated with body mass loss. Our aim...
Published in: | Applied Physiology, Nutrition, and Metabolism |
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crcansciencepubl:10.1139/apnm-2014-0418 2024-06-23T07:47:10+00:00 Nutritional status and the gonadotrophic response to a polar expedition Woods, David R. Delves, Simon K. Britland, Sophie E. Shaw, Anneliese Brown, Piete E. Bentley, Conor Hornby, Simon Burnett, Anne Lanham-New, Sue A. Fallowfield, Joanne L. 2015 http://dx.doi.org/10.1139/apnm-2014-0418 http://www.nrcresearchpress.com/doi/full-xml/10.1139/apnm-2014-0418 http://www.nrcresearchpress.com/doi/pdf/10.1139/apnm-2014-0418 en eng Canadian Science Publishing http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining Applied Physiology, Nutrition, and Metabolism volume 40, issue 3, page 292-297 ISSN 1715-5312 1715-5320 journal-article 2015 crcansciencepubl https://doi.org/10.1139/apnm-2014-0418 2024-06-13T04:10:50Z Polar expeditions have been associated with changes in the hypothalamic–pituitary–testicular axis consistent with central hypogonadism (i.e., decreased testosterone, luteinising hormone (LH), and follicle stimulating hormone (FSH)). These changes are typically associated with body mass loss. Our aim was to evaluate whether maintenance of body mass during a polar expedition could mitigate against the development of central hypogonadism. Male participants (n = 22) from a 42-day expedition (British Services Antarctic Expedition 2012) volunteered to take part in the study. Body mass, body composition, and strength data were recorded pre- and postexpedition in addition to assessment of serum testosterone, LH, FSH, thyroid hormones, insulin-like growth factor 1 (IGF-1), and trace elements. Energy provision and energy expenditure were assessed at mid- and end-expedition. Daily energy provision was 6335 ± 149 kcal·day −1 . Estimated energy expenditure midexpedition was 5783 ± 1690 kcal·day −1 . Body mass and percentage body fat did not change between pre- and postexpedition. Total testosterone (nmol·L −1 ) (14.0 ± 4.9 vs. 17.3 ± 4.0, p = 0.006), calculated free testosterone (pmol·L −1 ) (288 ± 82 vs. 350 ± 70, p = 0.003), and sex hormone binding globulin (nmol·L −1 ) (33 ± 12 vs. 36 ± 11, p = 0.023) concentrations increased. LH and FSH remained unchanged. Thyroid stimulating hormone (TSH; IU·L −1 ) (2.1 ± 0.8 vs. 4.1 ± 2.1, p < 0.001) and free triiodothyronine (FT3; IU·L −1 ) (5.4 ± 0.4 vs. 6.1 ± 0.8, p < 0.001) increased while free thyroxine, IGF-1, and trace elements remained unchanged. Hand-grip strength was reduced postexpedition but static lift strength was maintained. Maintenance of body mass and nutritional status appeared to negate the central hypogonadism previously reported from polar expeditions. The elevated TSH and free FT3 were consistent with a previously reported “polar T3 syndrome”. Article in Journal/Newspaper Antarc* Antarctic Canadian Science Publishing Antarctic Applied Physiology, Nutrition, and Metabolism 40 3 292 297 |
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Open Polar |
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Canadian Science Publishing |
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crcansciencepubl |
language |
English |
description |
Polar expeditions have been associated with changes in the hypothalamic–pituitary–testicular axis consistent with central hypogonadism (i.e., decreased testosterone, luteinising hormone (LH), and follicle stimulating hormone (FSH)). These changes are typically associated with body mass loss. Our aim was to evaluate whether maintenance of body mass during a polar expedition could mitigate against the development of central hypogonadism. Male participants (n = 22) from a 42-day expedition (British Services Antarctic Expedition 2012) volunteered to take part in the study. Body mass, body composition, and strength data were recorded pre- and postexpedition in addition to assessment of serum testosterone, LH, FSH, thyroid hormones, insulin-like growth factor 1 (IGF-1), and trace elements. Energy provision and energy expenditure were assessed at mid- and end-expedition. Daily energy provision was 6335 ± 149 kcal·day −1 . Estimated energy expenditure midexpedition was 5783 ± 1690 kcal·day −1 . Body mass and percentage body fat did not change between pre- and postexpedition. Total testosterone (nmol·L −1 ) (14.0 ± 4.9 vs. 17.3 ± 4.0, p = 0.006), calculated free testosterone (pmol·L −1 ) (288 ± 82 vs. 350 ± 70, p = 0.003), and sex hormone binding globulin (nmol·L −1 ) (33 ± 12 vs. 36 ± 11, p = 0.023) concentrations increased. LH and FSH remained unchanged. Thyroid stimulating hormone (TSH; IU·L −1 ) (2.1 ± 0.8 vs. 4.1 ± 2.1, p < 0.001) and free triiodothyronine (FT3; IU·L −1 ) (5.4 ± 0.4 vs. 6.1 ± 0.8, p < 0.001) increased while free thyroxine, IGF-1, and trace elements remained unchanged. Hand-grip strength was reduced postexpedition but static lift strength was maintained. Maintenance of body mass and nutritional status appeared to negate the central hypogonadism previously reported from polar expeditions. The elevated TSH and free FT3 were consistent with a previously reported “polar T3 syndrome”. |
format |
Article in Journal/Newspaper |
author |
Woods, David R. Delves, Simon K. Britland, Sophie E. Shaw, Anneliese Brown, Piete E. Bentley, Conor Hornby, Simon Burnett, Anne Lanham-New, Sue A. Fallowfield, Joanne L. |
spellingShingle |
Woods, David R. Delves, Simon K. Britland, Sophie E. Shaw, Anneliese Brown, Piete E. Bentley, Conor Hornby, Simon Burnett, Anne Lanham-New, Sue A. Fallowfield, Joanne L. Nutritional status and the gonadotrophic response to a polar expedition |
author_facet |
Woods, David R. Delves, Simon K. Britland, Sophie E. Shaw, Anneliese Brown, Piete E. Bentley, Conor Hornby, Simon Burnett, Anne Lanham-New, Sue A. Fallowfield, Joanne L. |
author_sort |
Woods, David R. |
title |
Nutritional status and the gonadotrophic response to a polar expedition |
title_short |
Nutritional status and the gonadotrophic response to a polar expedition |
title_full |
Nutritional status and the gonadotrophic response to a polar expedition |
title_fullStr |
Nutritional status and the gonadotrophic response to a polar expedition |
title_full_unstemmed |
Nutritional status and the gonadotrophic response to a polar expedition |
title_sort |
nutritional status and the gonadotrophic response to a polar expedition |
publisher |
Canadian Science Publishing |
publishDate |
2015 |
url |
http://dx.doi.org/10.1139/apnm-2014-0418 http://www.nrcresearchpress.com/doi/full-xml/10.1139/apnm-2014-0418 http://www.nrcresearchpress.com/doi/pdf/10.1139/apnm-2014-0418 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
Applied Physiology, Nutrition, and Metabolism volume 40, issue 3, page 292-297 ISSN 1715-5312 1715-5320 |
op_rights |
http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining |
op_doi |
https://doi.org/10.1139/apnm-2014-0418 |
container_title |
Applied Physiology, Nutrition, and Metabolism |
container_volume |
40 |
container_issue |
3 |
container_start_page |
292 |
op_container_end_page |
297 |
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1802651260824846336 |