Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992
Abstract Objective: To review experience with methicillin -resistant Staphylococcus aureus (MRSA) in tertiary acute-care teaching hospitals on the Canadian prairies. Design: Retrospective review for a 36-month period, 1990 through 1992. Setting: Five tertiary acute-care teaching hospitals in three C...
Published in: | Infection Control & Hospital Epidemiology |
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Language: | English |
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Cambridge University Press (CUP)
1994
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Online Access: | http://dx.doi.org/10.1086/646827 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S019594170000103X |
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crcambridgeupr:10.1086/646827 2024-06-23T07:52:51+00:00 Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 Embil, J. Ramotar, K. Romance, L. Alfa, M. Conly, J. Cronk, S. Taylor, G. Sutherland, B. Louie, T. Henderson, E. Nicolle, L.E. 1994 http://dx.doi.org/10.1086/646827 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S019594170000103X en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Infection Control & Hospital Epidemiology volume 15, issue 10, page 646-651 ISSN 0899-823X 1559-6834 journal-article 1994 crcambridgeupr https://doi.org/10.1086/646827 2024-06-05T04:04:09Z Abstract Objective: To review experience with methicillin -resistant Staphylococcus aureus (MRSA) in tertiary acute-care teaching hospitals on the Canadian prairies. Design: Retrospective review for a 36-month period, 1990 through 1992. Setting: Five tertiary acute-care teaching hospitals in three Canadian prairie provinces. Methods: MRSA isolates and susceptibility were identified through the clinical microbiology laboratory at each institution. For each patient, data collected included duration of institutional residence prior to isolation, patient ethnic background, age, sex, and antimicrobial susceptibility. Epidemiologic typing of strains used restriction fragment length polymorphism analysis by pulsed-field gel electrophoresis. Results: Two hundred fifty-nine MRSA isolates were identified in 135 patients during the 36 months, with substantial institutional variation in number of isolates. No consistent increase in yearly numbers of isolates was apparent. Patients usually had MRSA identified at admission (62%); only one of five centers had the majority of isolates acquired nosocomially. Patients with MRSA present at admission were more frequently of aboriginal (First Nations) ethnicity (62% compared with 14% of nosocomial; P<0.001). Pulsed-field gel electrophoresis of 167 isolates from 135 patients revealed 46 different strains with little interprovincial or inter-institutional identity of strains. Conclusions: MRSA isolated in patients in tertiary care institutions in these three Canadian provinces usually is acquired prior to admission. A disproportionate number of isolates are identified in aboriginal Canadians. Epidemiologic typing was consistent with a polyclonal origin of MRSA in this geographic area. Article in Journal/Newspaper First Nations Cambridge University Press Infection Control & Hospital Epidemiology 15 10 646 651 |
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Cambridge University Press |
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English |
description |
Abstract Objective: To review experience with methicillin -resistant Staphylococcus aureus (MRSA) in tertiary acute-care teaching hospitals on the Canadian prairies. Design: Retrospective review for a 36-month period, 1990 through 1992. Setting: Five tertiary acute-care teaching hospitals in three Canadian prairie provinces. Methods: MRSA isolates and susceptibility were identified through the clinical microbiology laboratory at each institution. For each patient, data collected included duration of institutional residence prior to isolation, patient ethnic background, age, sex, and antimicrobial susceptibility. Epidemiologic typing of strains used restriction fragment length polymorphism analysis by pulsed-field gel electrophoresis. Results: Two hundred fifty-nine MRSA isolates were identified in 135 patients during the 36 months, with substantial institutional variation in number of isolates. No consistent increase in yearly numbers of isolates was apparent. Patients usually had MRSA identified at admission (62%); only one of five centers had the majority of isolates acquired nosocomially. Patients with MRSA present at admission were more frequently of aboriginal (First Nations) ethnicity (62% compared with 14% of nosocomial; P<0.001). Pulsed-field gel electrophoresis of 167 isolates from 135 patients revealed 46 different strains with little interprovincial or inter-institutional identity of strains. Conclusions: MRSA isolated in patients in tertiary care institutions in these three Canadian provinces usually is acquired prior to admission. A disproportionate number of isolates are identified in aboriginal Canadians. Epidemiologic typing was consistent with a polyclonal origin of MRSA in this geographic area. |
format |
Article in Journal/Newspaper |
author |
Embil, J. Ramotar, K. Romance, L. Alfa, M. Conly, J. Cronk, S. Taylor, G. Sutherland, B. Louie, T. Henderson, E. Nicolle, L.E. |
spellingShingle |
Embil, J. Ramotar, K. Romance, L. Alfa, M. Conly, J. Cronk, S. Taylor, G. Sutherland, B. Louie, T. Henderson, E. Nicolle, L.E. Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
author_facet |
Embil, J. Ramotar, K. Romance, L. Alfa, M. Conly, J. Cronk, S. Taylor, G. Sutherland, B. Louie, T. Henderson, E. Nicolle, L.E. |
author_sort |
Embil, J. |
title |
Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
title_short |
Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
title_full |
Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
title_fullStr |
Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
title_full_unstemmed |
Methicillin-Resistant Staphylococcus aureus in Tertiary Care Institutions of the Canadian Prairies 1990-1992 |
title_sort |
methicillin-resistant staphylococcus aureus in tertiary care institutions of the canadian prairies 1990-1992 |
publisher |
Cambridge University Press (CUP) |
publishDate |
1994 |
url |
http://dx.doi.org/10.1086/646827 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S019594170000103X |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Infection Control & Hospital Epidemiology volume 15, issue 10, page 646-651 ISSN 0899-823X 1559-6834 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1086/646827 |
container_title |
Infection Control & Hospital Epidemiology |
container_volume |
15 |
container_issue |
10 |
container_start_page |
646 |
op_container_end_page |
651 |
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1802644270921809920 |