Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes
Abstract Objective The present study sought to investigate the associations of total n -3 fatty acid and SFA intakes with insulin resistance in a Canadian First Nation sample at risk for type 2 diabetes. Design Fasting values for glucose and insulin were used to estimate insulin resistance by homeos...
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Cambridge University Press (CUP)
2013
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Online Access: | http://dx.doi.org/10.1017/s1368980013000542 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1368980013000542 |
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crcambridgeupr:10.1017/s1368980013000542 2024-06-23T07:52:52+00:00 Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes Paquet, Catherine Propsting, Sarah L Daniel, Mark 2013 http://dx.doi.org/10.1017/s1368980013000542 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1368980013000542 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Public Health Nutrition volume 17, issue 6, page 1337-1341 ISSN 1368-9800 1475-2727 journal-article 2013 crcambridgeupr https://doi.org/10.1017/s1368980013000542 2024-06-12T04:04:17Z Abstract Objective The present study sought to investigate the associations of total n -3 fatty acid and SFA intakes with insulin resistance in a Canadian First Nation sample at risk for type 2 diabetes. Design Fasting values for glucose and insulin were used to estimate insulin resistance by homeostasis model assessment (HOMA-IR). Intakes of n -3 fatty acids and SFA were computed from dietary food and drink data obtained using 3 d food records. Associations between HOMA-IR and dietary n -3 and SFA consumption were tested using linear regression models accounting for age, sex, community, education, physical activity, waist circumference, fibre, protein and carbohydrate intakes, and HDL-cholesterol and TAG concentrations. Setting Rural Okanagan region of British Columbia, Canada. Subjects On-reserve First Nation individuals (Interior Salishan) aged 18 years and over, recruited for community-based diabetes screening and determined to be normoglycaemic ( n 126). Results HOMA-IR was negatively associated with dietary n -3 fatty acid intake ( β = −0·22; 95 % CI −0·39, −0·04; P = 0·016) and positively associated with dietary SFA intake ( β = 0·34; 95 % CI 0·15, 0·53; P = 0·0 0 1). Conclusions Intake of dietary n -3 fatty acids may be protective against whereas SFA intake may promote insulin resistance in this high-risk Canadian First Nation sample. Reduced dietary SFA intake and greater n -3 fatty acid intake may assist the prevention of glycaemic disease among First Nations peoples. More rigorous, controlled trials are required to test whether dietary supplementation with n -3 fatty acids in natural or supplement-based form might reduce diabetes risk in high-risk aboriginal groups. Article in Journal/Newspaper First Nations Cambridge University Press British Columbia ENVELOPE(-125.003,-125.003,54.000,54.000) Canada Public Health Nutrition 17 6 1337 1341 |
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Cambridge University Press |
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English |
description |
Abstract Objective The present study sought to investigate the associations of total n -3 fatty acid and SFA intakes with insulin resistance in a Canadian First Nation sample at risk for type 2 diabetes. Design Fasting values for glucose and insulin were used to estimate insulin resistance by homeostasis model assessment (HOMA-IR). Intakes of n -3 fatty acids and SFA were computed from dietary food and drink data obtained using 3 d food records. Associations between HOMA-IR and dietary n -3 and SFA consumption were tested using linear regression models accounting for age, sex, community, education, physical activity, waist circumference, fibre, protein and carbohydrate intakes, and HDL-cholesterol and TAG concentrations. Setting Rural Okanagan region of British Columbia, Canada. Subjects On-reserve First Nation individuals (Interior Salishan) aged 18 years and over, recruited for community-based diabetes screening and determined to be normoglycaemic ( n 126). Results HOMA-IR was negatively associated with dietary n -3 fatty acid intake ( β = −0·22; 95 % CI −0·39, −0·04; P = 0·016) and positively associated with dietary SFA intake ( β = 0·34; 95 % CI 0·15, 0·53; P = 0·0 0 1). Conclusions Intake of dietary n -3 fatty acids may be protective against whereas SFA intake may promote insulin resistance in this high-risk Canadian First Nation sample. Reduced dietary SFA intake and greater n -3 fatty acid intake may assist the prevention of glycaemic disease among First Nations peoples. More rigorous, controlled trials are required to test whether dietary supplementation with n -3 fatty acids in natural or supplement-based form might reduce diabetes risk in high-risk aboriginal groups. |
format |
Article in Journal/Newspaper |
author |
Paquet, Catherine Propsting, Sarah L Daniel, Mark |
spellingShingle |
Paquet, Catherine Propsting, Sarah L Daniel, Mark Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
author_facet |
Paquet, Catherine Propsting, Sarah L Daniel, Mark |
author_sort |
Paquet, Catherine |
title |
Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
title_short |
Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
title_full |
Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
title_fullStr |
Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
title_full_unstemmed |
Totaln-3 fatty acid and SFA intakes in relation to insulin resistance in a Canadian First Nation at risk for the development of type 2 diabetes |
title_sort |
totaln-3 fatty acid and sfa intakes in relation to insulin resistance in a canadian first nation at risk for the development of type 2 diabetes |
publisher |
Cambridge University Press (CUP) |
publishDate |
2013 |
url |
http://dx.doi.org/10.1017/s1368980013000542 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1368980013000542 |
long_lat |
ENVELOPE(-125.003,-125.003,54.000,54.000) |
geographic |
British Columbia Canada |
geographic_facet |
British Columbia Canada |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Public Health Nutrition volume 17, issue 6, page 1337-1341 ISSN 1368-9800 1475-2727 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s1368980013000542 |
container_title |
Public Health Nutrition |
container_volume |
17 |
container_issue |
6 |
container_start_page |
1337 |
op_container_end_page |
1341 |
_version_ |
1802644279835754496 |