Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus )
Abstract Man-animal relationships are involved in the process of fox domestication. Handling being an important part of man-animal contacts, causes stress responses in farm-bred blue foxes. The purpose of this study was to determine how prenatal stress induced by handling pregnant vixens influences...
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2003
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crcambridgeupr:10.1017/s135772980005863x 2023-05-15T13:19:53+02:00 Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) Osadchuk, L. V. Braastad, B. O. Hovland, A. L. Bakken, M. 2003 http://dx.doi.org/10.1017/s135772980005863x https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S135772980005863X en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Animal Science volume 76, issue 3, page 413-420 ISSN 1357-7298 1748-748X Animal Science and Zoology journal-article 2003 crcambridgeupr https://doi.org/10.1017/s135772980005863x 2022-08-23T16:55:48Z Abstract Man-animal relationships are involved in the process of fox domestication. Handling being an important part of man-animal contacts, causes stress responses in farm-bred blue foxes. The purpose of this study was to determine how prenatal stress induced by handling pregnant vixens influences certain morphometric and hormonal parameters of adrenocortical and gonadal function in the prepubertal offspring. Blue fox females were subjected to daily handling sessions, each of 1 min, in the last trimester of pregnancy (term = 52 days). Plasma concentrations of ACTH, cortisol, progesterone, oestradiol and testosterone, as well as the in vitro adrenal and gonadal production of steroids were measured by radio-immunoassay in control (C, no. = 56) and prenatally stressed (PS, no. = 56) blue fox cubs of both sexes at the age of 6 to 7 months. Prenatal stress decreased plasma concentration of cortisol (C: 31·0 (s.e. 4·3) v. PS: 22·7(s.e. 1·6) ng/ml, P < 0·05) as well as progesterone (C: 1·00(s.e. 0·10) v. PS: 0·65(s.e. 0·05) ng/ml, P < 0·05) in female cubs. Prenatal stress did not cause any changes in adrenal or gonadal weights, plasma concentrations of testosterone or oestradiol, or in vitro adrenal or gonadal steroid production, in either sex. It is concluded that persistent handling of pregnant blue foxes did not affect the prepubertal development of the reproductive system but resulted in disregulation in the hypothalamic-pituitary-adrenal axis in the female offspring. Article in Journal/Newspaper Alopex lagopus Cambridge University Press (via Crossref) Animal Science 76 3 413 420 |
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Cambridge University Press (via Crossref) |
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English |
topic |
Animal Science and Zoology |
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Animal Science and Zoology Osadchuk, L. V. Braastad, B. O. Hovland, A. L. Bakken, M. Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
topic_facet |
Animal Science and Zoology |
description |
Abstract Man-animal relationships are involved in the process of fox domestication. Handling being an important part of man-animal contacts, causes stress responses in farm-bred blue foxes. The purpose of this study was to determine how prenatal stress induced by handling pregnant vixens influences certain morphometric and hormonal parameters of adrenocortical and gonadal function in the prepubertal offspring. Blue fox females were subjected to daily handling sessions, each of 1 min, in the last trimester of pregnancy (term = 52 days). Plasma concentrations of ACTH, cortisol, progesterone, oestradiol and testosterone, as well as the in vitro adrenal and gonadal production of steroids were measured by radio-immunoassay in control (C, no. = 56) and prenatally stressed (PS, no. = 56) blue fox cubs of both sexes at the age of 6 to 7 months. Prenatal stress decreased plasma concentration of cortisol (C: 31·0 (s.e. 4·3) v. PS: 22·7(s.e. 1·6) ng/ml, P < 0·05) as well as progesterone (C: 1·00(s.e. 0·10) v. PS: 0·65(s.e. 0·05) ng/ml, P < 0·05) in female cubs. Prenatal stress did not cause any changes in adrenal or gonadal weights, plasma concentrations of testosterone or oestradiol, or in vitro adrenal or gonadal steroid production, in either sex. It is concluded that persistent handling of pregnant blue foxes did not affect the prepubertal development of the reproductive system but resulted in disregulation in the hypothalamic-pituitary-adrenal axis in the female offspring. |
format |
Article in Journal/Newspaper |
author |
Osadchuk, L. V. Braastad, B. O. Hovland, A. L. Bakken, M. |
author_facet |
Osadchuk, L. V. Braastad, B. O. Hovland, A. L. Bakken, M. |
author_sort |
Osadchuk, L. V. |
title |
Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
title_short |
Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
title_full |
Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
title_fullStr |
Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
title_full_unstemmed |
Reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( Alopex lagopus ) |
title_sort |
reproductive and pituitary-adrenal axis parameters in normal and prenatally stressed prepubertal blue foxes ( alopex lagopus ) |
publisher |
Cambridge University Press (CUP) |
publishDate |
2003 |
url |
http://dx.doi.org/10.1017/s135772980005863x https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S135772980005863X |
genre |
Alopex lagopus |
genre_facet |
Alopex lagopus |
op_source |
Animal Science volume 76, issue 3, page 413-420 ISSN 1357-7298 1748-748X |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s135772980005863x |
container_title |
Animal Science |
container_volume |
76 |
container_issue |
3 |
container_start_page |
413 |
op_container_end_page |
420 |
_version_ |
1766350049725382656 |