Impact of the harsh Antarctic environment on mucosal immunity
Abstract Mucosal immunity of Indian Antarctic personnel was analysed during the 34th Indian Scientific Expedition to Antarctica (ISEA) by ship voyage. Serum and salivary IgA, IgA1 and IgA2 levels along with salivary cortisol and TGF-β were quantified by enzyme-linked immunosorbent assay. Samples wer...
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crcambridgeupr:10.1017/s0954102021000407 2024-03-03T08:38:38+00:00 Impact of the harsh Antarctic environment on mucosal immunity Bhushan, Brij Tanwar, Himanshi Eslavath, Malleswara Rao Singh, Shashi Bala Kumar, Bhuvnesh Ganju, Lilly 2021 http://dx.doi.org/10.1017/s0954102021000407 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954102021000407 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Antarctic Science volume 33, issue 6, page 624-632 ISSN 0954-1020 1365-2079 Geology Ecology, Evolution, Behavior and Systematics Oceanography journal-article 2021 crcambridgeupr https://doi.org/10.1017/s0954102021000407 2024-02-08T08:31:58Z Abstract Mucosal immunity of Indian Antarctic personnel was analysed during the 34th Indian Scientific Expedition to Antarctica (ISEA) by ship voyage. Serum and salivary IgA, IgA1 and IgA2 levels along with salivary cortisol and TGF-β were quantified by enzyme-linked immunosorbent assay. Samples were collected at three different time points (T1, T2 and T3) during the expedition. Serum and salivary IgA, IgA1 and IgA2 concentrations incrementally increased towards the end of the expedition as compared to the beginning of the expedition. Salivary IgA and TGF-β levels were significantly altered during the expedition. Levels of IgA1 ( P = 0.0007) and IgA2 ( P = 0.0135) increased significantly at T3 as compared to T1. Additionally, significant changes in serum IgA were observed, with peak levels at T3 ( P = 0.0015) and T2 ( P < 0.001). However, the level of serum IgA2 was also significantly altered at T3 ( P < 0.05) and T2 ( P = 0.0006) in comparison with T1. The exact cause of the changes in serum and salivary IgA, IgA1, IgA2 and TGF-β levels during the summer expedition are unknown; however, the changes are evident in mucosal immunity. Article in Journal/Newspaper Antarc* Antarctic Antarctic Science Antarctica Cambridge University Press Antarctic Indian Antarctic Science 1 9 |
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Open Polar |
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Cambridge University Press |
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crcambridgeupr |
language |
English |
topic |
Geology Ecology, Evolution, Behavior and Systematics Oceanography |
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Geology Ecology, Evolution, Behavior and Systematics Oceanography Bhushan, Brij Tanwar, Himanshi Eslavath, Malleswara Rao Singh, Shashi Bala Kumar, Bhuvnesh Ganju, Lilly Impact of the harsh Antarctic environment on mucosal immunity |
topic_facet |
Geology Ecology, Evolution, Behavior and Systematics Oceanography |
description |
Abstract Mucosal immunity of Indian Antarctic personnel was analysed during the 34th Indian Scientific Expedition to Antarctica (ISEA) by ship voyage. Serum and salivary IgA, IgA1 and IgA2 levels along with salivary cortisol and TGF-β were quantified by enzyme-linked immunosorbent assay. Samples were collected at three different time points (T1, T2 and T3) during the expedition. Serum and salivary IgA, IgA1 and IgA2 concentrations incrementally increased towards the end of the expedition as compared to the beginning of the expedition. Salivary IgA and TGF-β levels were significantly altered during the expedition. Levels of IgA1 ( P = 0.0007) and IgA2 ( P = 0.0135) increased significantly at T3 as compared to T1. Additionally, significant changes in serum IgA were observed, with peak levels at T3 ( P = 0.0015) and T2 ( P < 0.001). However, the level of serum IgA2 was also significantly altered at T3 ( P < 0.05) and T2 ( P = 0.0006) in comparison with T1. The exact cause of the changes in serum and salivary IgA, IgA1, IgA2 and TGF-β levels during the summer expedition are unknown; however, the changes are evident in mucosal immunity. |
format |
Article in Journal/Newspaper |
author |
Bhushan, Brij Tanwar, Himanshi Eslavath, Malleswara Rao Singh, Shashi Bala Kumar, Bhuvnesh Ganju, Lilly |
author_facet |
Bhushan, Brij Tanwar, Himanshi Eslavath, Malleswara Rao Singh, Shashi Bala Kumar, Bhuvnesh Ganju, Lilly |
author_sort |
Bhushan, Brij |
title |
Impact of the harsh Antarctic environment on mucosal immunity |
title_short |
Impact of the harsh Antarctic environment on mucosal immunity |
title_full |
Impact of the harsh Antarctic environment on mucosal immunity |
title_fullStr |
Impact of the harsh Antarctic environment on mucosal immunity |
title_full_unstemmed |
Impact of the harsh Antarctic environment on mucosal immunity |
title_sort |
impact of the harsh antarctic environment on mucosal immunity |
publisher |
Cambridge University Press (CUP) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1017/s0954102021000407 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954102021000407 |
geographic |
Antarctic Indian |
geographic_facet |
Antarctic Indian |
genre |
Antarc* Antarctic Antarctic Science Antarctica |
genre_facet |
Antarc* Antarctic Antarctic Science Antarctica |
op_source |
Antarctic Science volume 33, issue 6, page 624-632 ISSN 0954-1020 1365-2079 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s0954102021000407 |
container_title |
Antarctic Science |
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9 |
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1792507046737739776 |