Antitumoural activity in Antarctic and sub-Antarctic benthic organisms
Abstract A prospecting search for antitumoural activity in polar benthic invertebrates was conducted on Antarctic and sub-Antarctic benthos in three different areas: Bouvet Island (sub-Antarctic), eastern Weddell Sea (Antarctica) and the South Shetland Islands (Antarctica). A total of 770 benthic in...
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crcambridgeupr:10.1017/s0954102010000416 2024-03-03T08:37:54+00:00 Antitumoural activity in Antarctic and sub-Antarctic benthic organisms Taboada, Sergi García-Fernández, Luis Francisco Bueno, Santiago Vázquez, Jennifer Cuevas, Carmen Avila, Conxita 2010 http://dx.doi.org/10.1017/s0954102010000416 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954102010000416 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Antarctic Science volume 22, issue 5, page 494-507 ISSN 0954-1020 1365-2079 Geology Ecology, Evolution, Behavior and Systematics Oceanography journal-article 2010 crcambridgeupr https://doi.org/10.1017/s0954102010000416 2024-02-08T08:39:48Z Abstract A prospecting search for antitumoural activity in polar benthic invertebrates was conducted on Antarctic and sub-Antarctic benthos in three different areas: Bouvet Island (sub-Antarctic), eastern Weddell Sea (Antarctica) and the South Shetland Islands (Antarctica). A total of 770 benthic invertebrate samples (corresponding to at least 290 different species) from 12 different phyla were assayed to establish their pharmacological potential against three human tumour cell lines (colorectal adenocarcinoma, lung carcinoma and breast adenocarcinoma). Bioassays resulted in 15 different species showing anticancer activity corresponding to five different phyla: Tunicata (5), Porifera (4), Cnidaria (3), Echinodermata (2) and Annelida (1). This appears to be the largest pharmacological study ever carried out in Antarctica and it shows very promising antitumoural activities in the Antarctic and sub-Antarctic benthos. Article in Journal/Newspaper Antarc* Antarctic Antarctic Science Antarctica Bouvet Island South Shetland Islands Weddell Sea Cambridge University Press Antarctic The Antarctic Weddell Sea South Shetland Islands Weddell Bouvet ENVELOPE(3.358,3.358,-54.422,-54.422) Bouvet Island ENVELOPE(3.358,3.358,-54.422,-54.422) Antarctic Science 22 5 494 507 |
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Open Polar |
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Cambridge University Press |
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crcambridgeupr |
language |
English |
topic |
Geology Ecology, Evolution, Behavior and Systematics Oceanography |
spellingShingle |
Geology Ecology, Evolution, Behavior and Systematics Oceanography Taboada, Sergi García-Fernández, Luis Francisco Bueno, Santiago Vázquez, Jennifer Cuevas, Carmen Avila, Conxita Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
topic_facet |
Geology Ecology, Evolution, Behavior and Systematics Oceanography |
description |
Abstract A prospecting search for antitumoural activity in polar benthic invertebrates was conducted on Antarctic and sub-Antarctic benthos in three different areas: Bouvet Island (sub-Antarctic), eastern Weddell Sea (Antarctica) and the South Shetland Islands (Antarctica). A total of 770 benthic invertebrate samples (corresponding to at least 290 different species) from 12 different phyla were assayed to establish their pharmacological potential against three human tumour cell lines (colorectal adenocarcinoma, lung carcinoma and breast adenocarcinoma). Bioassays resulted in 15 different species showing anticancer activity corresponding to five different phyla: Tunicata (5), Porifera (4), Cnidaria (3), Echinodermata (2) and Annelida (1). This appears to be the largest pharmacological study ever carried out in Antarctica and it shows very promising antitumoural activities in the Antarctic and sub-Antarctic benthos. |
format |
Article in Journal/Newspaper |
author |
Taboada, Sergi García-Fernández, Luis Francisco Bueno, Santiago Vázquez, Jennifer Cuevas, Carmen Avila, Conxita |
author_facet |
Taboada, Sergi García-Fernández, Luis Francisco Bueno, Santiago Vázquez, Jennifer Cuevas, Carmen Avila, Conxita |
author_sort |
Taboada, Sergi |
title |
Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
title_short |
Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
title_full |
Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
title_fullStr |
Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
title_full_unstemmed |
Antitumoural activity in Antarctic and sub-Antarctic benthic organisms |
title_sort |
antitumoural activity in antarctic and sub-antarctic benthic organisms |
publisher |
Cambridge University Press (CUP) |
publishDate |
2010 |
url |
http://dx.doi.org/10.1017/s0954102010000416 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954102010000416 |
long_lat |
ENVELOPE(3.358,3.358,-54.422,-54.422) ENVELOPE(3.358,3.358,-54.422,-54.422) |
geographic |
Antarctic The Antarctic Weddell Sea South Shetland Islands Weddell Bouvet Bouvet Island |
geographic_facet |
Antarctic The Antarctic Weddell Sea South Shetland Islands Weddell Bouvet Bouvet Island |
genre |
Antarc* Antarctic Antarctic Science Antarctica Bouvet Island South Shetland Islands Weddell Sea |
genre_facet |
Antarc* Antarctic Antarctic Science Antarctica Bouvet Island South Shetland Islands Weddell Sea |
op_source |
Antarctic Science volume 22, issue 5, page 494-507 ISSN 0954-1020 1365-2079 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s0954102010000416 |
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Antarctic Science |
container_volume |
22 |
container_issue |
5 |
container_start_page |
494 |
op_container_end_page |
507 |
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1792502616918327296 |