Studies of respiratory viruses in personnel at an Antarctic base
SUMMARY Thirteen men wintering on an Antarctic base were isolated from other human contact for 10 months. During this period Coxsackievirus A21 and later influenza A2 virus were administered to some of the men. Serum samples were collected from each of the men at monthly intervals. Coxsackievirus A2...
Published in: | Journal of Hygiene |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Cambridge University Press (CUP)
1971
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1017/s0022172400021422 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0022172400021422 |
id |
crcambridgeupr:10.1017/s0022172400021422 |
---|---|
record_format |
openpolar |
spelling |
crcambridgeupr:10.1017/s0022172400021422 2024-03-03T08:38:10+00:00 Studies of respiratory viruses in personnel at an Antarctic base Holmes, M. J. Allen, T. R. Bradburne, A. F. Stott, E. J. 1971 http://dx.doi.org/10.1017/s0022172400021422 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0022172400021422 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Journal of Hygiene volume 69, issue 2, page 187-199 ISSN 0022-1724 Public Health, Environmental and Occupational Health Immunology journal-article 1971 crcambridgeupr https://doi.org/10.1017/s0022172400021422 2024-02-08T08:37:41Z SUMMARY Thirteen men wintering on an Antarctic base were isolated from other human contact for 10 months. During this period Coxsackievirus A21 and later influenza A2 virus were administered to some of the men. Serum samples were collected from each of the men at monthly intervals. Coxsackievirus A21 produced symptoms and apparently spread to uninoculated men. It also appears that repeated re-infections occurred and that the virus persisted in this small community for most of the period of isolation. HI antibody responses in the absence of neutralizing antibody responses seem to be transient. The vaccine strain of influenza virus induced antibody responses but did not cause symptoms. There was no evidence of spread to uninoculated men. Antibody titres against influenza C, parainfluenzaviruses 1 and 2 and coronavirus OC43 did not fall significantly during isolation. An outbreak of respiratory illness occurred at the end of isolation and its origin was traced. No causative agent was detected. Article in Journal/Newspaper Antarc* Antarctic Cambridge University Press Antarctic Journal of Hygiene 69 2 187 199 |
institution |
Open Polar |
collection |
Cambridge University Press |
op_collection_id |
crcambridgeupr |
language |
English |
topic |
Public Health, Environmental and Occupational Health Immunology |
spellingShingle |
Public Health, Environmental and Occupational Health Immunology Holmes, M. J. Allen, T. R. Bradburne, A. F. Stott, E. J. Studies of respiratory viruses in personnel at an Antarctic base |
topic_facet |
Public Health, Environmental and Occupational Health Immunology |
description |
SUMMARY Thirteen men wintering on an Antarctic base were isolated from other human contact for 10 months. During this period Coxsackievirus A21 and later influenza A2 virus were administered to some of the men. Serum samples were collected from each of the men at monthly intervals. Coxsackievirus A21 produced symptoms and apparently spread to uninoculated men. It also appears that repeated re-infections occurred and that the virus persisted in this small community for most of the period of isolation. HI antibody responses in the absence of neutralizing antibody responses seem to be transient. The vaccine strain of influenza virus induced antibody responses but did not cause symptoms. There was no evidence of spread to uninoculated men. Antibody titres against influenza C, parainfluenzaviruses 1 and 2 and coronavirus OC43 did not fall significantly during isolation. An outbreak of respiratory illness occurred at the end of isolation and its origin was traced. No causative agent was detected. |
format |
Article in Journal/Newspaper |
author |
Holmes, M. J. Allen, T. R. Bradburne, A. F. Stott, E. J. |
author_facet |
Holmes, M. J. Allen, T. R. Bradburne, A. F. Stott, E. J. |
author_sort |
Holmes, M. J. |
title |
Studies of respiratory viruses in personnel at an Antarctic base |
title_short |
Studies of respiratory viruses in personnel at an Antarctic base |
title_full |
Studies of respiratory viruses in personnel at an Antarctic base |
title_fullStr |
Studies of respiratory viruses in personnel at an Antarctic base |
title_full_unstemmed |
Studies of respiratory viruses in personnel at an Antarctic base |
title_sort |
studies of respiratory viruses in personnel at an antarctic base |
publisher |
Cambridge University Press (CUP) |
publishDate |
1971 |
url |
http://dx.doi.org/10.1017/s0022172400021422 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0022172400021422 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
Journal of Hygiene volume 69, issue 2, page 187-199 ISSN 0022-1724 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s0022172400021422 |
container_title |
Journal of Hygiene |
container_volume |
69 |
container_issue |
2 |
container_start_page |
187 |
op_container_end_page |
199 |
_version_ |
1792505083034861568 |