High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.)
Replacing dietary fishmeal (FM) and fish oil (FO) with plant ingredients in Atlantic salmon ( Salmo salar L.) diets decreases dietary cholesterol and introduces phytosterols. The aim of the present study was to assess the effect of dietary sterol composition on cholesterol metabolism in Atlantic sal...
Published in: | British Journal of Nutrition |
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Online Access: | http://dx.doi.org/10.1017/s0007114513001347 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114513001347 |
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crcambridgeupr:10.1017/s0007114513001347 2024-10-06T13:47:15+00:00 High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) Liland, Nina S. Espe, Marit Rosenlund, Grethe Waagbø, Rune Hjelle, Jan I. Lie, Øyvind Fontanillas, Ramon Torstensen, Bente E. 2013 http://dx.doi.org/10.1017/s0007114513001347 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114513001347 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms British Journal of Nutrition volume 110, issue 11, page 1958-1967 ISSN 0007-1145 1475-2662 journal-article 2013 crcambridgeupr https://doi.org/10.1017/s0007114513001347 2024-09-11T04:04:44Z Replacing dietary fishmeal (FM) and fish oil (FO) with plant ingredients in Atlantic salmon ( Salmo salar L.) diets decreases dietary cholesterol and introduces phytosterols. The aim of the present study was to assess the effect of dietary sterol composition on cholesterol metabolism in Atlantic salmon. For this purpose, two dietary trials were performed, in which Atlantic salmon were fed either 100 % FM and FO (FM-FO) diet or one of the three diets with either high (80 %) or medium (40 %) plant protein (PP) and a high (70 %) or medium (35 %) vegetable oil (VO) blend (trial 1); or 70 % PP with either 100 % FO or 80 % of the FO replaced with olive, rapeseed or soyabean oil (trial 2). Replacing ≥ 70 % of FM with PP and ≥ 70 % of FO with either a VO blend or rapeseed oil increased plasma and liver TAG concentrations. These diets contained high levels of phytosterols and low levels of cholesterol. Fish fed low-cholesterol diets, but with less phytosterols, exhibited an increased expression of genes encoding proteins involved in cholesterol uptake and synthesis. The expression of these genes was, however, partially inhibited in rapeseed oil-fed fish possibly due to the high dietary and tissue phytosterol:cholesterol ratio. Atlantic salmon tissue and plasma cholesterol concentrations were maintained stable independent of the dietary sterol content. Article in Journal/Newspaper Atlantic salmon Salmo salar Cambridge University Press British Journal of Nutrition 110 11 1958 1967 |
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Cambridge University Press |
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crcambridgeupr |
language |
English |
description |
Replacing dietary fishmeal (FM) and fish oil (FO) with plant ingredients in Atlantic salmon ( Salmo salar L.) diets decreases dietary cholesterol and introduces phytosterols. The aim of the present study was to assess the effect of dietary sterol composition on cholesterol metabolism in Atlantic salmon. For this purpose, two dietary trials were performed, in which Atlantic salmon were fed either 100 % FM and FO (FM-FO) diet or one of the three diets with either high (80 %) or medium (40 %) plant protein (PP) and a high (70 %) or medium (35 %) vegetable oil (VO) blend (trial 1); or 70 % PP with either 100 % FO or 80 % of the FO replaced with olive, rapeseed or soyabean oil (trial 2). Replacing ≥ 70 % of FM with PP and ≥ 70 % of FO with either a VO blend or rapeseed oil increased plasma and liver TAG concentrations. These diets contained high levels of phytosterols and low levels of cholesterol. Fish fed low-cholesterol diets, but with less phytosterols, exhibited an increased expression of genes encoding proteins involved in cholesterol uptake and synthesis. The expression of these genes was, however, partially inhibited in rapeseed oil-fed fish possibly due to the high dietary and tissue phytosterol:cholesterol ratio. Atlantic salmon tissue and plasma cholesterol concentrations were maintained stable independent of the dietary sterol content. |
format |
Article in Journal/Newspaper |
author |
Liland, Nina S. Espe, Marit Rosenlund, Grethe Waagbø, Rune Hjelle, Jan I. Lie, Øyvind Fontanillas, Ramon Torstensen, Bente E. |
spellingShingle |
Liland, Nina S. Espe, Marit Rosenlund, Grethe Waagbø, Rune Hjelle, Jan I. Lie, Øyvind Fontanillas, Ramon Torstensen, Bente E. High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
author_facet |
Liland, Nina S. Espe, Marit Rosenlund, Grethe Waagbø, Rune Hjelle, Jan I. Lie, Øyvind Fontanillas, Ramon Torstensen, Bente E. |
author_sort |
Liland, Nina S. |
title |
High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
title_short |
High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
title_full |
High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
title_fullStr |
High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
title_full_unstemmed |
High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon ( Salmo salar L.) |
title_sort |
high levels of dietary phytosterols affect lipid metabolism and increase liver and plasma tag in atlantic salmon ( salmo salar l.) |
publisher |
Cambridge University Press (CUP) |
publishDate |
2013 |
url |
http://dx.doi.org/10.1017/s0007114513001347 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114513001347 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
British Journal of Nutrition volume 110, issue 11, page 1958-1967 ISSN 0007-1145 1475-2662 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s0007114513001347 |
container_title |
British Journal of Nutrition |
container_volume |
110 |
container_issue |
11 |
container_start_page |
1958 |
op_container_end_page |
1967 |
_version_ |
1812175480062738432 |