P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022
Background: Considering regional and temporal trends, we sought to explore the incidence of primary malignant brain tumours in Newfoundland and Labrador. Methods: We reviewed all primary, malignant brain tumour cases from 2015-2022 confirmed by St. John’s Health Sciences Centre pathology reports. In...
Published in: | Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques |
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Online Access: | http://dx.doi.org/10.1017/cjn.2024.199 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0317167124001999 |
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crcambridgeupr:10.1017/cjn.2024.199 2024-06-23T07:54:44+00:00 P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 Boone, LA Kazerouni, A Noble, T Barron, J Avery, R 2024 http://dx.doi.org/10.1017/cjn.2024.199 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0317167124001999 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques volume 51, issue s1, page S42-S42 ISSN 0317-1671 2057-0155 journal-article 2024 crcambridgeupr https://doi.org/10.1017/cjn.2024.199 2024-05-29T08:09:21Z Background: Considering regional and temporal trends, we sought to explore the incidence of primary malignant brain tumours in Newfoundland and Labrador. Methods: We reviewed all primary, malignant brain tumour cases from 2015-2022 confirmed by St. John’s Health Sciences Centre pathology reports. Incidence rates were standardized using the 2011 Canadian standard population. Results: We included 362 cases. The average annual age-standardized incidence rate of primary, malignant brain tumours per 100,000 was 7.0 (95% CI: 6.3-7.7), lower than the national average (7.93; 95% CI: 7.78-8.08). The incidence of glioblastoma (5.1; 95% CI: 4.5-5.7) was significantly higher than the national average (4.05; 95% CI: 3.95-4.16). Temporal trends revealed that oligodendroglioma incidence spiked from 0.5 (95% CI: 0.2-0.7) in 2015-2019 to 1.5 (95% CI: 0.4-2.6) in 2020 before returning to baseline in 2022. Regional trends indicated a lower incidence of malignant tumours in Labrador-Grenfell (5.1; 95% CI: 2.5-7.6), compared to 6.9 (95% CI: 6.2-7.6) averaged elsewhere. Conclusions: Higher rates of glioblastoma in Newfoundland and Labrador could have a genetic or multi-factorial cause. The increased occurrence of oligodendroglioma during the COVID-19 pandemic necessitates broader investigation, potentially linked to delays in patient care during this period. Regional trends could suggest less access to care in rural populations and underestimated incidence. Article in Journal/Newspaper Newfoundland Cambridge University Press Newfoundland Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 51 s1 S42 S42 |
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Cambridge University Press |
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crcambridgeupr |
language |
English |
description |
Background: Considering regional and temporal trends, we sought to explore the incidence of primary malignant brain tumours in Newfoundland and Labrador. Methods: We reviewed all primary, malignant brain tumour cases from 2015-2022 confirmed by St. John’s Health Sciences Centre pathology reports. Incidence rates were standardized using the 2011 Canadian standard population. Results: We included 362 cases. The average annual age-standardized incidence rate of primary, malignant brain tumours per 100,000 was 7.0 (95% CI: 6.3-7.7), lower than the national average (7.93; 95% CI: 7.78-8.08). The incidence of glioblastoma (5.1; 95% CI: 4.5-5.7) was significantly higher than the national average (4.05; 95% CI: 3.95-4.16). Temporal trends revealed that oligodendroglioma incidence spiked from 0.5 (95% CI: 0.2-0.7) in 2015-2019 to 1.5 (95% CI: 0.4-2.6) in 2020 before returning to baseline in 2022. Regional trends indicated a lower incidence of malignant tumours in Labrador-Grenfell (5.1; 95% CI: 2.5-7.6), compared to 6.9 (95% CI: 6.2-7.6) averaged elsewhere. Conclusions: Higher rates of glioblastoma in Newfoundland and Labrador could have a genetic or multi-factorial cause. The increased occurrence of oligodendroglioma during the COVID-19 pandemic necessitates broader investigation, potentially linked to delays in patient care during this period. Regional trends could suggest less access to care in rural populations and underestimated incidence. |
format |
Article in Journal/Newspaper |
author |
Boone, LA Kazerouni, A Noble, T Barron, J Avery, R |
spellingShingle |
Boone, LA Kazerouni, A Noble, T Barron, J Avery, R P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
author_facet |
Boone, LA Kazerouni, A Noble, T Barron, J Avery, R |
author_sort |
Boone, LA |
title |
P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
title_short |
P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
title_full |
P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
title_fullStr |
P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
title_full_unstemmed |
P.094 Incidence of pathologically confirmed primary malignant brain tumours in Newfoundland and Labrador: an eight-year review spanning 2015-2022 |
title_sort |
p.094 incidence of pathologically confirmed primary malignant brain tumours in newfoundland and labrador: an eight-year review spanning 2015-2022 |
publisher |
Cambridge University Press (CUP) |
publishDate |
2024 |
url |
http://dx.doi.org/10.1017/cjn.2024.199 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0317167124001999 |
geographic |
Newfoundland |
geographic_facet |
Newfoundland |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques volume 51, issue s1, page S42-S42 ISSN 0317-1671 2057-0155 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/cjn.2024.199 |
container_title |
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques |
container_volume |
51 |
container_issue |
s1 |
container_start_page |
S42 |
op_container_end_page |
S42 |
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1802646987910152192 |