P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador
Background: There is a paucity of research regarding ALS epidemiology in Canada. Previously published data from Newfoundland and Labrador (NL) demonstrate an average incidence of 2.4/100,000 from 2000-2004 (peak 3.3 in 2001, the highest reported in Canada). Local neurologists believe that the incide...
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crcambridgeupr:10.1017/cjn.2019.127 2024-03-03T08:46:42+00:00 P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador Aminian, KS Whelan, G Murphy, D Stefanelli, M 2019 http://dx.doi.org/10.1017/cjn.2019.127 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0317167119001276 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques volume 46, issue s1, page S21 ISSN 0317-1671 2057-0155 Neurology (clinical) Neurology General Medicine journal-article 2019 crcambridgeupr https://doi.org/10.1017/cjn.2019.127 2024-02-08T08:48:16Z Background: There is a paucity of research regarding ALS epidemiology in Canada. Previously published data from Newfoundland and Labrador (NL) demonstrate an average incidence of 2.4/100,000 from 2000-2004 (peak 3.3 in 2001, the highest reported in Canada). Local neurologists believe that the incidence has continued to increase. Methods: Clinicians affiliated with the electromyography (EMG) lab at the Health Sciences Centre in St. John’s compiled a list of patients diagnosed with ALS from 2012-2016, based on recall. Their medical records were reviewed and demographic information collected. This was cross-referenced with new referrals to the ALS Society NL per year. Results: Based on new referrals to ALS Society NL the average incidence between 2012-2016 was 2.81/100,000 (peak 3.6 in 2015). Average age-adjusted incidence from the EMG lab was 1.33 (peak 1.73 in 2016). The EMG lab documented a crude incidence of 3.97 in 2018. Conclusions: The incidence of ALS in NL is increased compared to the usual incidence of 1-2/100,000 per year. After the preliminary study, the EMG lab maintained more thorough records and an incidence of 3.97/100,000 was found in 2018. This makes a compelling argument for future research which could explore potential genetic or environmental causes for the increased incidence in this population. Article in Journal/Newspaper Newfoundland Cambridge University Press Newfoundland Canada Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 46 s1 S21 |
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Cambridge University Press |
op_collection_id |
crcambridgeupr |
language |
English |
topic |
Neurology (clinical) Neurology General Medicine |
spellingShingle |
Neurology (clinical) Neurology General Medicine Aminian, KS Whelan, G Murphy, D Stefanelli, M P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
topic_facet |
Neurology (clinical) Neurology General Medicine |
description |
Background: There is a paucity of research regarding ALS epidemiology in Canada. Previously published data from Newfoundland and Labrador (NL) demonstrate an average incidence of 2.4/100,000 from 2000-2004 (peak 3.3 in 2001, the highest reported in Canada). Local neurologists believe that the incidence has continued to increase. Methods: Clinicians affiliated with the electromyography (EMG) lab at the Health Sciences Centre in St. John’s compiled a list of patients diagnosed with ALS from 2012-2016, based on recall. Their medical records were reviewed and demographic information collected. This was cross-referenced with new referrals to the ALS Society NL per year. Results: Based on new referrals to ALS Society NL the average incidence between 2012-2016 was 2.81/100,000 (peak 3.6 in 2015). Average age-adjusted incidence from the EMG lab was 1.33 (peak 1.73 in 2016). The EMG lab documented a crude incidence of 3.97 in 2018. Conclusions: The incidence of ALS in NL is increased compared to the usual incidence of 1-2/100,000 per year. After the preliminary study, the EMG lab maintained more thorough records and an incidence of 3.97/100,000 was found in 2018. This makes a compelling argument for future research which could explore potential genetic or environmental causes for the increased incidence in this population. |
format |
Article in Journal/Newspaper |
author |
Aminian, KS Whelan, G Murphy, D Stefanelli, M |
author_facet |
Aminian, KS Whelan, G Murphy, D Stefanelli, M |
author_sort |
Aminian, KS |
title |
P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
title_short |
P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
title_full |
P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
title_fullStr |
P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
title_full_unstemmed |
P.027 Incidence of amyotrophic lateral sclerosis in Newfoundland and Labrador |
title_sort |
p.027 incidence of amyotrophic lateral sclerosis in newfoundland and labrador |
publisher |
Cambridge University Press (CUP) |
publishDate |
2019 |
url |
http://dx.doi.org/10.1017/cjn.2019.127 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0317167119001276 |
geographic |
Newfoundland Canada |
geographic_facet |
Newfoundland Canada |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques volume 46, issue s1, page S21 ISSN 0317-1671 2057-0155 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/cjn.2019.127 |
container_title |
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques |
container_volume |
46 |
container_issue |
s1 |
container_start_page |
S21 |
_version_ |
1792502750420926464 |