FURTHER OBSERVATIONS ON THE ADRENAL SECRETORY RHYTHM OF THE BROWN LEMMING

• Published in: Acta Endocrinologica
• Main Authors: Andrews, Richard V., Keil, Lanny C., Keil, Nancy Nolder
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Bioscientifica 1968
• Subjects: Endocrinology; General Medicine; Endocrinology, Diabetes and Metabolism; Arctic
• Online Access: http://dx.doi.org/10.1530/acta.0.0590036; https://eje.bioscientifica.com/view/journals/eje/59/1/acta_59_1_004.xml

ABSTRACT Isolated lemming adrenals display daily rhythms which persist for at least five days when the glands are maintained in organ culture. Rhythmic corticosteroid secretion in vitro shows a »free running« period of less than 24 hours (23.4 ± 0.2 hours). When the intervals of animal sacrifice in culture experiments overlap, initial peaks displayed by glands from the freshly killed donor animals are in phase with peaks of five-day cultures; these data are interpreted as evidence for »free running« periodicity in adrenal function of lemmings exposed to the arctic day.