Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray
ABSTRACT The emergence of viruses such as severe acute respiratory syndrome coronavirus and Nipah virus has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a panviral DNA microarray to investigate the death of a captive beluga whale i...
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American Society for Microbiology
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Online Access: | http://dx.doi.org/10.1128/jvi.02722-07 https://journals.asm.org/doi/pdf/10.1128/JVI.02722-07 |
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crasmicro:10.1128/jvi.02722-07 2024-10-13T14:06:21+00:00 Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray Mihindukulasuriya, Kathie A. Wu, Guang St. Leger, Judy Nordhausen, Robert W. Wang, David 2008 http://dx.doi.org/10.1128/jvi.02722-07 https://journals.asm.org/doi/pdf/10.1128/JVI.02722-07 en eng American Society for Microbiology https://journals.asm.org/non-commercial-tdm-license Journal of Virology volume 82, issue 10, page 5084-5088 ISSN 0022-538X 1098-5514 journal-article 2008 crasmicro https://doi.org/10.1128/jvi.02722-07 2024-09-23T04:07:49Z ABSTRACT The emergence of viruses such as severe acute respiratory syndrome coronavirus and Nipah virus has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a panviral DNA microarray to investigate the death of a captive beluga whale in an aquatic park. A highly divergent coronavirus, tentatively named coronavirus SW1, was identified in liver tissue from the deceased whale. Subsequently, the entire genome of SW1 was sequenced, yielding a genome of 31,686 nucleotides. Phylogenetic analysis revealed SW1 to be a novel virus distantly related to but most similar to group III coronaviruses. Article in Journal/Newspaper Beluga Beluga whale Beluga* ASM Journals (American Society for Microbiology) Journal of Virology 82 10 5084 5088 |
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ASM Journals (American Society for Microbiology) |
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language |
English |
description |
ABSTRACT The emergence of viruses such as severe acute respiratory syndrome coronavirus and Nipah virus has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a panviral DNA microarray to investigate the death of a captive beluga whale in an aquatic park. A highly divergent coronavirus, tentatively named coronavirus SW1, was identified in liver tissue from the deceased whale. Subsequently, the entire genome of SW1 was sequenced, yielding a genome of 31,686 nucleotides. Phylogenetic analysis revealed SW1 to be a novel virus distantly related to but most similar to group III coronaviruses. |
format |
Article in Journal/Newspaper |
author |
Mihindukulasuriya, Kathie A. Wu, Guang St. Leger, Judy Nordhausen, Robert W. Wang, David |
spellingShingle |
Mihindukulasuriya, Kathie A. Wu, Guang St. Leger, Judy Nordhausen, Robert W. Wang, David Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
author_facet |
Mihindukulasuriya, Kathie A. Wu, Guang St. Leger, Judy Nordhausen, Robert W. Wang, David |
author_sort |
Mihindukulasuriya, Kathie A. |
title |
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
title_short |
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
title_full |
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
title_fullStr |
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
title_full_unstemmed |
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray |
title_sort |
identification of a novel coronavirus from a beluga whale by using a panviral microarray |
publisher |
American Society for Microbiology |
publishDate |
2008 |
url |
http://dx.doi.org/10.1128/jvi.02722-07 https://journals.asm.org/doi/pdf/10.1128/JVI.02722-07 |
genre |
Beluga Beluga whale Beluga* |
genre_facet |
Beluga Beluga whale Beluga* |
op_source |
Journal of Virology volume 82, issue 10, page 5084-5088 ISSN 0022-538X 1098-5514 |
op_rights |
https://journals.asm.org/non-commercial-tdm-license |
op_doi |
https://doi.org/10.1128/jvi.02722-07 |
container_title |
Journal of Virology |
container_volume |
82 |
container_issue |
10 |
container_start_page |
5084 |
op_container_end_page |
5088 |
_version_ |
1812812464466690048 |