Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals
ABSTRACT The Paramyxoviridae form an increasingly diverse viral family, infecting a wide variety of different hosts. In recent years, they have been linked to disease emergence in many different animal populations and in humans. Bats and rodents have been identified as major animal populations capab...
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Online Access: | http://dx.doi.org/10.1128/jvi.01211-14 https://journals.asm.org/doi/pdf/10.1128/JVI.01211-14 |
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crasmicro:10.1128/jvi.01211-14 2024-06-23T07:56:24+00:00 Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals Wilkinson, David A. Mélade, Julien Dietrich, Muriel Ramasindrazana, Beza Soarimalala, Voahangy Lagadec, Erwan le Minter, Gildas Tortosa, Pablo Heraud, Jean-Michel de Lamballerie, Xavier Goodman, Steven M. Dellagi, Koussay Pascalis, Herve García-Sastre, A. 2014 http://dx.doi.org/10.1128/jvi.01211-14 https://journals.asm.org/doi/pdf/10.1128/JVI.01211-14 en eng American Society for Microbiology https://journals.asm.org/non-commercial-tdm-license Journal of Virology volume 88, issue 15, page 8268-8277 ISSN 0022-538X 1098-5514 journal-article 2014 crasmicro https://doi.org/10.1128/jvi.01211-14 2024-06-10T04:07:33Z ABSTRACT The Paramyxoviridae form an increasingly diverse viral family, infecting a wide variety of different hosts. In recent years, they have been linked to disease emergence in many different animal populations and in humans. Bats and rodents have been identified as major animal populations capable of harboring paramyxoviruses, and host shifting between these animals is likely to be an important driving factor in the underlying evolutionary processes that eventually lead to disease emergence. Here, we have studied paramyxovirus circulation within populations of endemic and introduced wild small mammals of the southwestern Indian Ocean region and belonging to four taxonomic orders: Rodentia, Afrosoricida, Soricomorpha, and Chiroptera. We report elevated infection levels as well as widespread paramyxovirus dispersal and frequent host exchange of a newly emerging genus of the Paramyxoviridae , currently referred to as the unclassified morbillivirus-related viruses (UMRVs). In contrast to other genera of the Paramyxoviridae , where bats have been shown to be a key host species, we show that rodents (and, in particular, Rattus rattus ) are significant spreaders of UMRVs. We predict that the ecological particularities of the southwestern Indian Ocean, where small mammal species often live in densely packed, multispecies communities, in combination with the increasing invasion of R. rattus and perturbations of endemic animal communities by active anthropological development, will have a major influence on the dynamics of UMRV infection. IMPORTANCE Identification of the infectious agents that circulate within wild animal reservoirs is essential for several reasons: (i) infectious disease outbreaks often originate from wild fauna; (ii) anthropological expansion increases the risk of contact between human and animal populations and, as a result, the risk of disease emergence; (iii) evaluation of pathogen reservoirs helps in elaborating preventive measures to limit the risk of disease emergence. Many paramyxoviruses for ... Article in Journal/Newspaper Rattus rattus ASM Journals (American Society for Microbiology) Indian Journal of Virology 88 15 8268 8277 |
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Open Polar |
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ASM Journals (American Society for Microbiology) |
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crasmicro |
language |
English |
description |
ABSTRACT The Paramyxoviridae form an increasingly diverse viral family, infecting a wide variety of different hosts. In recent years, they have been linked to disease emergence in many different animal populations and in humans. Bats and rodents have been identified as major animal populations capable of harboring paramyxoviruses, and host shifting between these animals is likely to be an important driving factor in the underlying evolutionary processes that eventually lead to disease emergence. Here, we have studied paramyxovirus circulation within populations of endemic and introduced wild small mammals of the southwestern Indian Ocean region and belonging to four taxonomic orders: Rodentia, Afrosoricida, Soricomorpha, and Chiroptera. We report elevated infection levels as well as widespread paramyxovirus dispersal and frequent host exchange of a newly emerging genus of the Paramyxoviridae , currently referred to as the unclassified morbillivirus-related viruses (UMRVs). In contrast to other genera of the Paramyxoviridae , where bats have been shown to be a key host species, we show that rodents (and, in particular, Rattus rattus ) are significant spreaders of UMRVs. We predict that the ecological particularities of the southwestern Indian Ocean, where small mammal species often live in densely packed, multispecies communities, in combination with the increasing invasion of R. rattus and perturbations of endemic animal communities by active anthropological development, will have a major influence on the dynamics of UMRV infection. IMPORTANCE Identification of the infectious agents that circulate within wild animal reservoirs is essential for several reasons: (i) infectious disease outbreaks often originate from wild fauna; (ii) anthropological expansion increases the risk of contact between human and animal populations and, as a result, the risk of disease emergence; (iii) evaluation of pathogen reservoirs helps in elaborating preventive measures to limit the risk of disease emergence. Many paramyxoviruses for ... |
author2 |
García-Sastre, A. |
format |
Article in Journal/Newspaper |
author |
Wilkinson, David A. Mélade, Julien Dietrich, Muriel Ramasindrazana, Beza Soarimalala, Voahangy Lagadec, Erwan le Minter, Gildas Tortosa, Pablo Heraud, Jean-Michel de Lamballerie, Xavier Goodman, Steven M. Dellagi, Koussay Pascalis, Herve |
spellingShingle |
Wilkinson, David A. Mélade, Julien Dietrich, Muriel Ramasindrazana, Beza Soarimalala, Voahangy Lagadec, Erwan le Minter, Gildas Tortosa, Pablo Heraud, Jean-Michel de Lamballerie, Xavier Goodman, Steven M. Dellagi, Koussay Pascalis, Herve Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
author_facet |
Wilkinson, David A. Mélade, Julien Dietrich, Muriel Ramasindrazana, Beza Soarimalala, Voahangy Lagadec, Erwan le Minter, Gildas Tortosa, Pablo Heraud, Jean-Michel de Lamballerie, Xavier Goodman, Steven M. Dellagi, Koussay Pascalis, Herve |
author_sort |
Wilkinson, David A. |
title |
Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
title_short |
Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
title_full |
Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
title_fullStr |
Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
title_full_unstemmed |
Highly Diverse Morbillivirus-Related Paramyxoviruses in Wild Fauna of the Southwestern Indian Ocean Islands: Evidence of Exchange between Introduced and Endemic Small Mammals |
title_sort |
highly diverse morbillivirus-related paramyxoviruses in wild fauna of the southwestern indian ocean islands: evidence of exchange between introduced and endemic small mammals |
publisher |
American Society for Microbiology |
publishDate |
2014 |
url |
http://dx.doi.org/10.1128/jvi.01211-14 https://journals.asm.org/doi/pdf/10.1128/JVI.01211-14 |
geographic |
Indian |
geographic_facet |
Indian |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Journal of Virology volume 88, issue 15, page 8268-8277 ISSN 0022-538X 1098-5514 |
op_rights |
https://journals.asm.org/non-commercial-tdm-license |
op_doi |
https://doi.org/10.1128/jvi.01211-14 |
container_title |
Journal of Virology |
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88 |
container_issue |
15 |
container_start_page |
8268 |
op_container_end_page |
8277 |
_version_ |
1802649475836018688 |