Increasing Incidence of Candidemia: Results from a 20-Year Nationwide Study in Iceland

• Published in: Journal of Clinical Microbiology
• Main Authors: Ásmundsdóttir, Lena Rós, Erlendsdóttir, Helga, Gottfredsson, Magnús
• Format: Article in Journal/Newspaper
• Language: English
• Published: American Society for Microbiology 2002
• Subjects: Iceland
• Online Access: http://dx.doi.org/10.1128/jcm.40.9.3489-3492.2002; https://journals.asm.org/doi/pdf/10.1128/JCM.40.9.3489-3492.2002

ABSTRACT A nationwide study on candidemia was conducted in Iceland from 1980 to 1999. The annual incidence increased from 1.4 cases/100,000 inhabitants/year between 1980 and 1984 to 4.9 cases/100,000 inhabitants/year between 1995 and 1999 ( P < 0.0001). Candidemia episodes at university hospitals increased from 0.15/1,000 admissions to 0.55/1,000 admissions ( P < 0.0001). Candida albicans was the predominant species responsible (64.4%). The national import of fluconazole increased approximately fourfold during the second half of the study, but increased resistance to this agent was not observed.