Meningococcal phenotypic and genotypic characteristics and human antibody levels
During a 2-month period in 1984, throat and blood samples were collected from 1,102 healthy persons of different ages living in the city of Tromsø, Norway. One hundred and eight persons (9.8%) were meningococcal carriers, but the carrier rate varied with sex and age. Twenty-nine isolates (26.9%) wer...
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American Society for Microbiology
1988
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crasmicro:10.1128/jcm.26.10.1988-1992.1988 2023-10-09T21:56:18+02:00 Meningococcal phenotypic and genotypic characteristics and human antibody levels Kristiansen, B E Lind, K W Mevold, K Sørensen, B Frøholm, L O Bryn, K Tjade, T Bøvre, K 1988 http://dx.doi.org/10.1128/jcm.26.10.1988-1992.1988 https://journals.asm.org/doi/pdf/10.1128/jcm.26.10.1988-1992.1988 en eng American Society for Microbiology https://journals.asm.org/non-commercial-tdm-license Journal of Clinical Microbiology volume 26, issue 10, page 1988-1992 ISSN 0095-1137 1098-660X Microbiology (medical) journal-article 1988 crasmicro https://doi.org/10.1128/jcm.26.10.1988-1992.1988 2023-09-15T05:46:14Z During a 2-month period in 1984, throat and blood samples were collected from 1,102 healthy persons of different ages living in the city of Tromsø, Norway. One hundred and eight persons (9.8%) were meningococcal carriers, but the carrier rate varied with sex and age. Twenty-nine isolates (26.9%) were of serogroup B, and 31 (28.7%) isolates contained the serotype 15 antigen. Sixty-eight (63.0%) isolates were nontypable, 49 (45.4%) were nongroupable, and 21 (19.4%) were sulfonamide resistant. All nine serotype 2a isolates and eight (25.8%) of the serotype 15 isolates were sulfonamide resistant. Only these eight serotype 15, sulfonamide-resistant isolates had a DNA fingerprint similar to that of the majority of systemic isolates of Neisseria meningitidis in Norway. The average level of antimeningococcal immunoglobulin G antibodies, as determined by a whole-bacterium enzyme immunoassay with a systemic B:15 meningococcal strain as the antigen, was low until 12 to 15 years of age and then steadily increased. Article in Journal/Newspaper Tromsø ASM Journals (American Society for Microbiology - via Crossref) Norway Tromsø Journal of Clinical Microbiology 26 10 1988 1992 |
institution |
Open Polar |
collection |
ASM Journals (American Society for Microbiology - via Crossref) |
op_collection_id |
crasmicro |
language |
English |
topic |
Microbiology (medical) |
spellingShingle |
Microbiology (medical) Kristiansen, B E Lind, K W Mevold, K Sørensen, B Frøholm, L O Bryn, K Tjade, T Bøvre, K Meningococcal phenotypic and genotypic characteristics and human antibody levels |
topic_facet |
Microbiology (medical) |
description |
During a 2-month period in 1984, throat and blood samples were collected from 1,102 healthy persons of different ages living in the city of Tromsø, Norway. One hundred and eight persons (9.8%) were meningococcal carriers, but the carrier rate varied with sex and age. Twenty-nine isolates (26.9%) were of serogroup B, and 31 (28.7%) isolates contained the serotype 15 antigen. Sixty-eight (63.0%) isolates were nontypable, 49 (45.4%) were nongroupable, and 21 (19.4%) were sulfonamide resistant. All nine serotype 2a isolates and eight (25.8%) of the serotype 15 isolates were sulfonamide resistant. Only these eight serotype 15, sulfonamide-resistant isolates had a DNA fingerprint similar to that of the majority of systemic isolates of Neisseria meningitidis in Norway. The average level of antimeningococcal immunoglobulin G antibodies, as determined by a whole-bacterium enzyme immunoassay with a systemic B:15 meningococcal strain as the antigen, was low until 12 to 15 years of age and then steadily increased. |
format |
Article in Journal/Newspaper |
author |
Kristiansen, B E Lind, K W Mevold, K Sørensen, B Frøholm, L O Bryn, K Tjade, T Bøvre, K |
author_facet |
Kristiansen, B E Lind, K W Mevold, K Sørensen, B Frøholm, L O Bryn, K Tjade, T Bøvre, K |
author_sort |
Kristiansen, B E |
title |
Meningococcal phenotypic and genotypic characteristics and human antibody levels |
title_short |
Meningococcal phenotypic and genotypic characteristics and human antibody levels |
title_full |
Meningococcal phenotypic and genotypic characteristics and human antibody levels |
title_fullStr |
Meningococcal phenotypic and genotypic characteristics and human antibody levels |
title_full_unstemmed |
Meningococcal phenotypic and genotypic characteristics and human antibody levels |
title_sort |
meningococcal phenotypic and genotypic characteristics and human antibody levels |
publisher |
American Society for Microbiology |
publishDate |
1988 |
url |
http://dx.doi.org/10.1128/jcm.26.10.1988-1992.1988 https://journals.asm.org/doi/pdf/10.1128/jcm.26.10.1988-1992.1988 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Journal of Clinical Microbiology volume 26, issue 10, page 1988-1992 ISSN 0095-1137 1098-660X |
op_rights |
https://journals.asm.org/non-commercial-tdm-license |
op_doi |
https://doi.org/10.1128/jcm.26.10.1988-1992.1988 |
container_title |
Journal of Clinical Microbiology |
container_volume |
26 |
container_issue |
10 |
container_start_page |
1988 |
op_container_end_page |
1992 |
_version_ |
1779320927366938624 |