Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer
ABSTRACT Members of the viral subfamily Alphaherpesvirinae establish latency from which they can be reactivated. Bovine herpesvirus 1 causes infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cattle, as well as abortion and weak calves. Serological evidence of alphaherpesvir...
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crasmicro:10.1128/jcm.02416-08 2024-09-15T18:06:13+00:00 Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer das Neves, Carlos G. Rimstad, Espen Tryland, Morten 2009 http://dx.doi.org/10.1128/jcm.02416-08 https://journals.asm.org/doi/pdf/10.1128/JCM.02416-08 en eng American Society for Microbiology https://journals.asm.org/non-commercial-tdm-license Journal of Clinical Microbiology volume 47, issue 5, page 1309-1313 ISSN 0095-1137 1098-660X journal-article 2009 crasmicro https://doi.org/10.1128/jcm.02416-08 2024-07-08T04:09:24Z ABSTRACT Members of the viral subfamily Alphaherpesvirinae establish latency from which they can be reactivated. Bovine herpesvirus 1 causes infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cattle, as well as abortion and weak calves. Serological evidence of alphaherpesvirus infection has been reported for wild and semidomesticated reindeer ( Rangifer tarandus tarandus ) in Norway. To address the possibility that reindeer alphaherpesvirus (cervid herpesvirus 2 [CvHV-2]) infection might affect the respiratory system and in part explain the relatively high mortality of reindeer calves during their first year, tissue samples were obtained from reindeer and reindeer fetuses at slaughterhouses in Finnmark County, Norway. A nested pan-alphaherpesvirus PCR amplification targeting the highly conserved UL27 gene (encoding glycoprotein B) was used. Sequencing of amplicons revealed the presence of CvHV-2 DNA. The detection of CvHV-2 DNA in trigeminal ganglia (27 of 143 samples), nasal swabs (5 of 75 samples), and fetal tissues (12 of 48 samples) indicates that CvHV-2 infection is endemic in this reindeer population. Moreover, the virus is transmitted horizontally by the respiratory route, establishing latency in the trigeminal ganglion, and vertically to the fetus through the placenta. Further studies should focus on the reproductive impact of CvHV-2 infection in reindeer. Article in Journal/Newspaper Finnmark Rangifer tarandus Finnmark ASM Journals (American Society for Microbiology) Journal of Clinical Microbiology 47 5 1309 1313 |
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English |
description |
ABSTRACT Members of the viral subfamily Alphaherpesvirinae establish latency from which they can be reactivated. Bovine herpesvirus 1 causes infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cattle, as well as abortion and weak calves. Serological evidence of alphaherpesvirus infection has been reported for wild and semidomesticated reindeer ( Rangifer tarandus tarandus ) in Norway. To address the possibility that reindeer alphaherpesvirus (cervid herpesvirus 2 [CvHV-2]) infection might affect the respiratory system and in part explain the relatively high mortality of reindeer calves during their first year, tissue samples were obtained from reindeer and reindeer fetuses at slaughterhouses in Finnmark County, Norway. A nested pan-alphaherpesvirus PCR amplification targeting the highly conserved UL27 gene (encoding glycoprotein B) was used. Sequencing of amplicons revealed the presence of CvHV-2 DNA. The detection of CvHV-2 DNA in trigeminal ganglia (27 of 143 samples), nasal swabs (5 of 75 samples), and fetal tissues (12 of 48 samples) indicates that CvHV-2 infection is endemic in this reindeer population. Moreover, the virus is transmitted horizontally by the respiratory route, establishing latency in the trigeminal ganglion, and vertically to the fetus through the placenta. Further studies should focus on the reproductive impact of CvHV-2 infection in reindeer. |
format |
Article in Journal/Newspaper |
author |
das Neves, Carlos G. Rimstad, Espen Tryland, Morten |
spellingShingle |
das Neves, Carlos G. Rimstad, Espen Tryland, Morten Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
author_facet |
das Neves, Carlos G. Rimstad, Espen Tryland, Morten |
author_sort |
das Neves, Carlos G. |
title |
Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
title_short |
Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
title_full |
Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
title_fullStr |
Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
title_full_unstemmed |
Cervid Herpesvirus 2 Causes Respiratory and Fetal Infections in Semidomesticated Reindeer |
title_sort |
cervid herpesvirus 2 causes respiratory and fetal infections in semidomesticated reindeer |
publisher |
American Society for Microbiology |
publishDate |
2009 |
url |
http://dx.doi.org/10.1128/jcm.02416-08 https://journals.asm.org/doi/pdf/10.1128/JCM.02416-08 |
genre |
Finnmark Rangifer tarandus Finnmark |
genre_facet |
Finnmark Rangifer tarandus Finnmark |
op_source |
Journal of Clinical Microbiology volume 47, issue 5, page 1309-1313 ISSN 0095-1137 1098-660X |
op_rights |
https://journals.asm.org/non-commercial-tdm-license |
op_doi |
https://doi.org/10.1128/jcm.02416-08 |
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Journal of Clinical Microbiology |
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47 |
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5 |
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1309 |
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1313 |
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1810443711590432768 |