Does DDT Inhibit Carbonic Anhydrase?
At a concentration of 50 to 100 micrograms per milliliter, p,p '-DDT (and p,p '-DDE) did not inhibit the rate of hydration or dehydration of carbon dioxide by carbonic anhydrase. At concentrations greater than 500 micrograms per milliliter, partial inhibition of the rate of dehydration of...
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American Association for the Advancement of Science (AAAS)
1971
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Online Access: | http://dx.doi.org/10.1126/science.172.3984.728 https://www.science.org/doi/pdf/10.1126/science.172.3984.728 |
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craaas:10.1126/science.172.3984.728 2024-06-09T07:45:20+00:00 Does DDT Inhibit Carbonic Anhydrase? Dvorchik, Barry H. Istin, Michael Maren, Thomas H. 1971 http://dx.doi.org/10.1126/science.172.3984.728 https://www.science.org/doi/pdf/10.1126/science.172.3984.728 en eng American Association for the Advancement of Science (AAAS) Science volume 172, issue 3984, page 728-729 ISSN 0036-8075 1095-9203 journal-article 1971 craaas https://doi.org/10.1126/science.172.3984.728 2024-05-16T12:55:29Z At a concentration of 50 to 100 micrograms per milliliter, p,p '-DDT (and p,p '-DDE) did not inhibit the rate of hydration or dehydration of carbon dioxide by carbonic anhydrase. At concentrations greater than 500 micrograms per milliliter, partial inhibition of the rate of dehydration of carbonic acid was observed, but this involved precipitation of drug in the reaction vessel. This degree of inhibition suggests that DDT may not inhibit carbonic anhydrase effectively at the usual concentrations found in tissue after exposure of organisms to DDT in the environment. Article in Journal/Newspaper Carbonic acid AAAS Resource Center (American Association for the Advancement of Science) Science 172 3984 728 729 |
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Open Polar |
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AAAS Resource Center (American Association for the Advancement of Science) |
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craaas |
language |
English |
description |
At a concentration of 50 to 100 micrograms per milliliter, p,p '-DDT (and p,p '-DDE) did not inhibit the rate of hydration or dehydration of carbon dioxide by carbonic anhydrase. At concentrations greater than 500 micrograms per milliliter, partial inhibition of the rate of dehydration of carbonic acid was observed, but this involved precipitation of drug in the reaction vessel. This degree of inhibition suggests that DDT may not inhibit carbonic anhydrase effectively at the usual concentrations found in tissue after exposure of organisms to DDT in the environment. |
format |
Article in Journal/Newspaper |
author |
Dvorchik, Barry H. Istin, Michael Maren, Thomas H. |
spellingShingle |
Dvorchik, Barry H. Istin, Michael Maren, Thomas H. Does DDT Inhibit Carbonic Anhydrase? |
author_facet |
Dvorchik, Barry H. Istin, Michael Maren, Thomas H. |
author_sort |
Dvorchik, Barry H. |
title |
Does DDT Inhibit Carbonic Anhydrase? |
title_short |
Does DDT Inhibit Carbonic Anhydrase? |
title_full |
Does DDT Inhibit Carbonic Anhydrase? |
title_fullStr |
Does DDT Inhibit Carbonic Anhydrase? |
title_full_unstemmed |
Does DDT Inhibit Carbonic Anhydrase? |
title_sort |
does ddt inhibit carbonic anhydrase? |
publisher |
American Association for the Advancement of Science (AAAS) |
publishDate |
1971 |
url |
http://dx.doi.org/10.1126/science.172.3984.728 https://www.science.org/doi/pdf/10.1126/science.172.3984.728 |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Science volume 172, issue 3984, page 728-729 ISSN 0036-8075 1095-9203 |
op_doi |
https://doi.org/10.1126/science.172.3984.728 |
container_title |
Science |
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172 |
container_issue |
3984 |
container_start_page |
728 |
op_container_end_page |
729 |
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1801374634938990592 |