Alpha-Glycerophosphate Dehydrogenase and Glucose-6-Phosphate Dehydrogenase in Tissues of the Weddell Seal

• Published in: Science
• Main Authors: Fried, George H., Ray, Carleton, Hiller, Jack, Rabinow, Steve, Antopol, William
• Format: Article in Journal/Newspaper
• Language: English
• Published: American Association for the Advancement of Science (AAAS) 1967
• Subjects: Weddell; Weddell Seal; Weddell Seals
• Online Access: http://dx.doi.org/10.1126/science.155.3769.1560; https://www.science.org/doi/pdf/10.1126/science.155.3769.1560

High activity of alpha-glycerophosphate dehydrogenase and low activity of glucose-6-phosphate dehydrogenase in adipose tissue of Weddell seals suggest that neutral fat may be assembled there from exogenous sources of fatty acids. Low activity of glucose-6-phosphate dehydrogenase in other tissues tested precludes assignment of the function of fatty-acid synthesis to any specific tissue and emphasizes uniqueness of adipose mass in seals.