Unique evolution of foraminiferal calcification to survive global changes
Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal response...
Published in: | Science Advances |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2023
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1126/sciadv.add3584 https://www.science.org/doi/pdf/10.1126/sciadv.add3584 |
id |
craaas:10.1126/sciadv.add3584 |
---|---|
record_format |
openpolar |
spelling |
craaas:10.1126/sciadv.add3584 2024-10-06T13:51:48+00:00 Unique evolution of foraminiferal calcification to survive global changes Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi 2023 http://dx.doi.org/10.1126/sciadv.add3584 https://www.science.org/doi/pdf/10.1126/sciadv.add3584 en eng American Association for the Advancement of Science (AAAS) Science Advances volume 9, issue 25 ISSN 2375-2548 journal-article 2023 craaas https://doi.org/10.1126/sciadv.add3584 2024-09-12T04:00:24Z Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal responses to ocean acidification, which alters marine calcium carbonate production, potentially leading to biogeochemical cycle changes. We conducted comparative single-cell transcriptomics and fluorescent microscopy and identified calcium ion (Ca 2+ ) transport/secretion genes and α-carbonic anhydrases that control calcification in a foraminifer. They actively take up Ca 2+ to boost mitochondrial adenosine triphosphate synthesis during calcification but need to pump excess intracellular Ca 2+ to the calcification site to prevent cell death. Unique α-carbonic anhydrase genes induce the generation of bicarbonate and proton from multiple CO 2 sources. These control mechanisms have evolved independently since the Precambrian to enable the development of large cells and calcification despite decreasing Ca 2+ concentrations and pH in seawater. The present findings provide previously unknown insights into the calcification mechanisms and their subsequent function in enduring ocean acidification. Article in Journal/Newspaper Ocean acidification AAAS Resource Center (American Association for the Advancement of Science) Science Advances 9 25 |
institution |
Open Polar |
collection |
AAAS Resource Center (American Association for the Advancement of Science) |
op_collection_id |
craaas |
language |
English |
description |
Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal responses to ocean acidification, which alters marine calcium carbonate production, potentially leading to biogeochemical cycle changes. We conducted comparative single-cell transcriptomics and fluorescent microscopy and identified calcium ion (Ca 2+ ) transport/secretion genes and α-carbonic anhydrases that control calcification in a foraminifer. They actively take up Ca 2+ to boost mitochondrial adenosine triphosphate synthesis during calcification but need to pump excess intracellular Ca 2+ to the calcification site to prevent cell death. Unique α-carbonic anhydrase genes induce the generation of bicarbonate and proton from multiple CO 2 sources. These control mechanisms have evolved independently since the Precambrian to enable the development of large cells and calcification despite decreasing Ca 2+ concentrations and pH in seawater. The present findings provide previously unknown insights into the calcification mechanisms and their subsequent function in enduring ocean acidification. |
format |
Article in Journal/Newspaper |
author |
Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi |
spellingShingle |
Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi Unique evolution of foraminiferal calcification to survive global changes |
author_facet |
Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi |
author_sort |
Ujiié, Yurika |
title |
Unique evolution of foraminiferal calcification to survive global changes |
title_short |
Unique evolution of foraminiferal calcification to survive global changes |
title_full |
Unique evolution of foraminiferal calcification to survive global changes |
title_fullStr |
Unique evolution of foraminiferal calcification to survive global changes |
title_full_unstemmed |
Unique evolution of foraminiferal calcification to survive global changes |
title_sort |
unique evolution of foraminiferal calcification to survive global changes |
publisher |
American Association for the Advancement of Science (AAAS) |
publishDate |
2023 |
url |
http://dx.doi.org/10.1126/sciadv.add3584 https://www.science.org/doi/pdf/10.1126/sciadv.add3584 |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_source |
Science Advances volume 9, issue 25 ISSN 2375-2548 |
op_doi |
https://doi.org/10.1126/sciadv.add3584 |
container_title |
Science Advances |
container_volume |
9 |
container_issue |
25 |
_version_ |
1812180096186843136 |