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Chemical Sciences not elsewhere classified Developmental Biology Ecology Medicine Pharmacology Physiology Space Science alkyl chain alkyl substituent amide groups chemical additives based different sizes effective additives ethylenediaminetetraacetic acid bisamides flow assurance applications foam formation form foam hydrate crystals hydrate decomposition compared hydrate escalated remarkably hydrophobic alkyl groups inhibition properties known ghp less toxic compared methane hydrate methane hydrate formation n </ new class nucleation time increased obtained results revealed