Search Results

Mycolactone induces cell death by SETD1B-dependent degradation of glutathione.

by Birgit Förster, Caroline Demangel, Thorsten Thye
Published in PLOS Neglected Tropical Diseases (2020)

Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organs.

by Hui Hong, Emmanuelle Coutanceau, Marion Leclerc, Laxmee Caleechurn, Peter F Leadlay, Caroline Demangel
Published in PLoS Neglected Tropical Diseases (2008)

Mycolactone displays anti-inflammatory effects on the nervous system.

by Caroline Isaac, Annie Mauborgne, Alfonso Grimaldi, Kemy Ade, Michel Pohl, Cristina Limatola, Yves Boucher, Caroline Demangel, Laure Guenin-Macé
Published in PLOS Neglected Tropical Diseases (2017)

Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer disease.

by Richard O Phillips, Fred S Sarfo, Jordi Landier, Reid Oldenburg, Michael Frimpong, Mark Wansbrough-Jones, Kabiru Abass, William Thompson, Mark Forson, Arnaud Fontanet, Fatoumata Niang, Caroline Demangel
Published in PLoS Neglected Tropical Diseases (2014)

Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system.

by Emma Colucci-Guyon, Aline Rifflet, Sarah Saint-Auret, Anaëlle da Costa, Laurent Boucontet, Thomas Laval, Christophe Prehaud, Nicolas Blanchard, Jean-Pierre Levraud, Ivo G Boneca, Caroline Demangel, Laure Guenin-Macé
Published in PLOS Neglected Tropical Diseases (2020)

Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.

by Fred S Sarfo, Fabien Le Chevalier, N'Guetta Aka, Richard O Phillips, Yaw Amoako, Ivo G Boneca, Pascal Lenormand, Mireille Dosso, Mark Wansbrough-Jones, Romain Veyron-Churlet, Laure Guenin-Macé, Caroline Demangel
Published in PLoS Neglected Tropical Diseases (2011)